Regarding bio-geographical perspective, Prokletije belong to Alpine – mountain region, which has also influenced the animal world, defined by great variety. The mountain is well-known for its wealth in invertebrates as well as its diversity of vertebrates.

Prokletije represent the most significant center of herpetofauna (herpetology). Of forty types of amphibians and reptiles spread across Prokletije, nine are endemic. Also, a large number of indigenous species of the range finish in this area.

Based on the information from ornithologists, 180 bird species are registered in this area, so it can be said that Prokletije belong to a group of mountain massifs with the richest ornithology fauna in Montenegro and wider. The number of mammals in this region, especially the presence of threatened and protected species, attracts the attention of many.